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Home Hemodialysis
Frequent and
Flexible
HomeFrequent and Short Home Hemodialysis
An Innovative Therapy
End-stage chronic kidney disease (ESKD) represents a major challenge in nephrology, requiring optimized therapeutic solutions to improve both patient quality of life and clinical outcomes.
Among the available options, frequent and short home hemodialysis (FHHD) emerges as an effective alternative to conventional in-center dialysis, offering both physiological benefits and significant improvements in quality of life.
- Improved quality of life10,11,12
- Favorable progression in terms of hemodynamics and cardiac complications1,15
- Better blood pressure control1,15
- Une tendance à l’amélioration de la survie8,9,16
- Reduced dietary restrictions, allowing for a less restrictive diet5,6
The user-friendly design of the S³ system, with its flexibility, efficiency, and safety features, makes it an excellent option for patients with chronic kidney disease (CKD) and end-stage renal disease (ESRD).
Principle and Functioning of Home Hemodialysis
Hemodialysis is based on the extracorporeal purification of blood through a hemodialyzer (or "artificial kidney"), allowing the removal of uremic toxins and excess fluids. In the context of frequent home hemodialysis, dialysis is performed several times per week (4 to 6 sessions), with shorter durations (2 to 3 hours per session).. This protocol offers a more physiological approach, reducing abrupt hemodynamic variations observed in conventional treatments (3 weekly sessions of 4 hours in a dialysis center).14The therapy is based on:- A preferred vascular access: an arteriovenous fistula (AVF) or a central venous catheter.
- A dialysis monitor ensuring precise control of blood flow and dialysate parameters.
- A hemodialyzer: with S³, it can be selected according to the patient's needs, optimizing tolerance and the removal of uremic toxins.
Clinical Benefits
of Frequent Home Hemodialysis
of Frequent Home Hemodialysis
Préservation et Amélioration du Système Cardiovasculaire
Cardiovascular complications are the leading cause of morbidity and mortality in dialysis patients. Frequent home hemodialysis (FHHD) contributes to better hemodynamic stability, particularly through:
A reduction in the ultrafiltration rate, associated with better dry weight control. 3,15
A rapid decrease in systolic and diastolic blood pressure, promoting the reduction or discontinuation of antihypertensive treatments.15
A decrease in the frequency of intradialytic hypotension, improving treatment tolerance.1
Improvement of Quality of Life
Frequent Home Hemodialysis promotes greater autonomy and a better integration of dialysis sessions into the patient's daily routine. It enables:
- A better post-dialysis recovery, with reduced fatigue12.
- Greater flexibility in scheduling sessions, improving treatment adherence10.
A reduction in professional and social constraints: 25% of patients on Frequent Home HemoDialysis regained employment during the RECAP study3.
Optimisation de l’État Nutritionnel
More frequent removal of metabolic waste improves the nutritional status of patients:- Better control of phosphatemia, potentially reducing the need for phosphate binders.4
- Significant increase in serum albumin levels, a key indicator of nutritional status.3
Reduction
of Dietary Restrictions
Unlike conventional hemodialysis, which requires strict control of potassium and fluid intake, FHHD:
- Allows for a more varied diet, improving overall nutritional intake.6
- Reduces constraints related to fluid and electrolyte restrictions5.
Diminution du Risque
de Mortalité et d’Hospitalisation
Frequent hemodialysis eliminates the two consecutive days without treatment, a known risk factor for mortality. It enhances hemodynamic stability and improves cardiovascular status. Several studies confirm a reduction in mortality risk.16.
It also leads to a reduction in hospitalization rates, particularly for cardiovascular reasons.17
Weinhandl ED, Liu J, Gilbertson DT, et al. Survival in daily home hemodialysis and matched thrice-weekly in-center hemodialysis patients. J Am Soc Nephrol. 2012, 23(5):895-904.
Advantages
Medico-Economic
Frequent Home Hemodialysis also offers significant economic benefits:
- Reduction in transportation and hospitalization costs due to home-based care.18
- Optimization of healthcare resource utilization, with a reduced need for medical staff in healthcare facilities.18
Physidia et la Solution S³
Un moniteur compact pour l’Hémodialyse à Domicile
The monitor S³ by Physidia is specifically designed for Frequent Home Hemodialysis, combining safety, performance, and ease of use :
- Intuitive interface, facilitating self-management by the patient.1
- Optimized technology for effective purification, notably through the prescriber’s free choice of hemodialyzer and the SeCoHD® (push-pull) modality, which enhances the removal of medium-sized toxins.4
- Real-time monitoring system and safety alarms, ensuring a reliable treatment5: PhysiNums®
Frequent and short home hemodialysis represents a major advancement in the management of patients with chronic kidney disease, offering a better quality of life, enhanced cardiovascular stability, and a reduction in complications associated with conventional dialysis.
Thanks to innovative solutions like the Physidia S³ monitor, this approach is becoming more accessible and secure, paving the way for a new era of personalized and optimized dialysis.
